Brain Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Brain Cancer, including details on symptoms, benign and malignant tumors, gliomas, treatment.

Cerebral neurocytoma without ganglion cell differentiation.

Kim JH, Park KJ, Lee JH, Chung HS

Department of Neurosurgery, School of Medicine, Korea University, Gurodong-gil, Guro-gu, Seoul, Korea.

Neurocytomas are rare neuronal tumours, and are defined as tumours comprising cells with neuronal differentiation; they commonly arise in the ventricles. We report a case of a cerebral neurocytoma in a young man who presented with hemiparesis. The tumour was a radiologically a well-circumscribed large cyst with solid mass; the histopathology showed a well-differentiated lesion comprising uniform, round cells with perinuclear halos in a neuropil background, and immunohistochemically positive for neuronal markers (synaptophysin, neuron-specific enolase and neurofilaments). We suggest that cerebral neurocytomas should be considered among the uncommon causes of a large intra-axial cystic mass with a solid component in young adults.

Published 2 June 2005 in Acta Neurochir (Wien), 147(3): 309-12; discussion 312.
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