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Pleomorphic xanthoastrocytoma of the cerebellum: illustrated review.

Gil-Gouveia R, Cristino N, Farias JP, Trindade A, Ruivo NS, Pimentel J

Laboratory of Neuropathology, Institute of Molecular Medicine, Hospital de Santa Maria, Lisboa, Portugal. rgilgouveia@simplesnet.com

Although rarely, the usually benign, supratentorial, grade II astrocytic tumour pleomorphic xanthoastrocytoma (PXA) may arise from the cerebellum. A review of the published cases of these PXAs is made including the author's own case of a 40 years-old man with a right cerebellopontine angle tumour, which recurred after a gross total resection. The major clinical and histopathological features of cerebellar PXAs are discussed, and factors playing a role in their biological behaviour, like post-surgical medical treatment, genetics and extent of leptomeningeal seeding are stressed.

Published 25 October 2004 in Acta Neurochir (Wien), 146(11): 1241-4.
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